Toby Flood has been ruled out of England's QBE autumn international against New Zealand with a toe injury, head coach Stuart Lancaster has confirmed.

The Leicester fly-half suffered ligament damage in the big toe of his right foot during England's 16-15 defeat to South Africa.

Owen Farrell, who came off the bench on Saturday, is set to take over at fly-half against the All Blacks with the uncapped Freddie Burns likely to be named on the bench when Lancaster confirms his 23-man squad on Thursday.