Legal moves are to be undertaken to shut down Dalton Grange.
Syngenta have asked lawyers to start legal proceedings to evict the tenants, Mike and Kim Dean, who have been running the building as a party venue for many years.
The building was previously home to the now-defunct Dalton Grange Social Club, a club for retired employees of what used to be ICI and Zeneca.
The club, wound up in 2012 after a decline in membership, allowed the Deans to trade from the building – while Syngenta continued to pay all the bills including business rates, heating, lighting, water and insurance.
Syngenta said the company had met annual running costs of £30,000, a total of £200,000 since 2011.
But now the chemical giant is to take decisive action.
Syngenta claims the firm picks up annual running costs for the building amounting to £30,000 and receives no income from the private hospitality and catering business operated from the premises.
The firm first asked for the premises to be vacated almost three years ago in 2013, but even though the former Dalton Grange Social Club was winding up, the occupants claimed that they had no legal obligation to do so and that they had no intention of leaving.
Carl Sykes of Syngenta said “We have been up front about our position from the outset, as far back as 2013. The Social Club no longer exists and there is no contractual agreement in place for running a private hospitality business. Syngenta has acted entirely reasonably and is not prepared to subsidise a private business any longer.
“The building is still being actively advertised as available for bookings, despite notice being given twice.”
Syngenta first gave notice in July 2013 and then again in November 2015 for the occupants to vacate the premises. Solicitors acting for the firm have been instructed to commence possession proceedings.
A post on the Dalton Grange facebook page in January 2016 reads “Are you thinking of celebrating a special event this year then please get in touch for our fantastic new year offers.”
Solicitor Phil Booth, representing Michael and Kim Dean said: "Since 2013 I have made it clear to Syngenta and their solicitors that my clients are entitled to continue to carry on their business. We have set out at length the legal reasons for this, and that my clients were going to carry on with the business to which they have devoted so much.
"It appears that Syngenta are determined to continue to bully my clients out. Their threats of demolition were thwarted, and I expect that there latest barrage will be. If Syngenta are now seriously going to proceed with the threats which they have been making so for so long, then Michael and Kim welcome the opportunity which this gives them to be vindicated by the Court."
Syngenta has withdrawn its application to demolish the Grade II listed building and the company has pledged to explore alternative uses for Dalton Grange when the building becomes vacant but said that any alternative use must support its manufacturing operations.