Two brothers aged two and three died in a house fire in Fartown, police have confirmed.
Firefighters were called to a semi-detached house in Alder Street at just after 2pm on Saturday.
A woman and another child aged six escaped the blaze but the two boys were trapped in a bedroom.
Fire crews rescued the two boys but they were pronounced dead a short time later.
Fire crews from Huddersfield Fire Station attended the scene and police were informed.
Officers closed a stretch of road between Red Doles Road and Tubby Lane as investigations began.
The cause of the fire is not thought to be suspicious.
In a statement West Yorkshire Police said: “Police were called to an address in Alder Street, Huddersfield, shortly before 2.15pm on Saturday after being made aware by West Yorkshire Fire and Rescue Service of a house fire with persons reported inside.
“A woman and a child, who had been in the property, had made their own way out prior to the arrival of the emergency services with fire crews removing two other children from the address. Both of these children were pronounced deceased a short time later.
“The children have yet to be formally identified but are believed to be two boys, aged two and three. Their next of kin have been made aware.
“Enquiries continue into the cause of the fire but at this time it is not believed to be of suspicious origin.”