DEFENDER Ian Hughes and midfielder Tony Carss were in the treatment room today after picking up knee injuries during Town's clash with Cheltenham.
Hughes took a knock shortly before half-time and didn't reappear for the second period, with Efe Sodje coming on.
Carss lasted until the 72nd minute before giving way to Rob Edwards, who made his first appearance since picking up a hamstring injury at Swansea in September.
Town's third substitution - centre-back Paul Scott's 79th-minute replacement by loan striker Fola Onibuje, who was making his senior debut after just a handful of outings for Preston Reserves, was tactical, with manager Peter Jackson trying to pep up his faltering attack.
"Hughes felt pain after making a tackle, while Carss has been carrying a niggle for a couple of weeks now," reported Jackson, who is waiting for an assessment of midfielder John Thorrington's ankle injury.
"It's a setback, but at least we have a free fortnight for them to get treatment."
Nineteen-year-old Onibuje will play in a private practice match against Grimsby tomorrow, and Jackson added: "It was good to get him on on Saturday, although he had little chance to impress.
"It's a big step-up - he's still eligible to play for the Juniors, don't forget - and people will have to be a little patient, but Fola has plenty of potential."
Town's home Reserve clash with Sheffield Wednesday will now take place on Wednesday, December 15 (2.00).