And BetVictor make the Terriers 17/10 favourites to seal all three points on home soil with the visitors 85/40 and the draw 2/1.
Both sides gained promotion from the SkyBet Championship last term and have made stellar starts to their debut seasons in the top-flight.
The Terriers were magnificent in the corresponding fixture last term, beating the Seagulls 3-1 in front of a buoyant home faithful, and will likewise need the John Smith's to be rocking to claim a much-needed win on Saturday.
Premier League Relegation prices from BetVictor currently are:
Swansea City - 1/4
West Ham United - 11/10
Huddersfield Town - 6/5
Crystal Palace - 6/4
West Bromwich Albion - 2/1
Brighton & Hove Albion - 7/2
Since October’s jaw-dropping defeat of Manchester United, Town have struggled with defeats to both Merseyside clubs book-ending a run of five defeats in six and just two goals scored within that sequence.
Steve Mounié is slowly but surely returning to full fitness and will give the hosts a much-needed focal point in the final third and remains BetVictor’s odds-on favourite to be the Terriers’ leading league goalscorer this term.
The forward is also 6/1 to break the deadlock on Saturday and 23/10 to net his first goal since his brace on the opening day of the PL campaign.
Huddersfield’s own ‘M and M’ will be pivotal to Town getting a result at the weekend, with Aaron Mooy over-priced at 4/1 with BetVictor to net anytime against the Albion.
Town were quick out of the traps in the 3-1 defeat of Brighton last season, netting three times before the interval, and I have a sneaking suspicion we will see history repeated in West Yorkshire.
Town are 4/1 with BetVictor to be leading at both half-time and full-time in the double result market and appeal at both that and at the 11/2 to win and both teams to score against a Brighton side now winless in their last four PL games.
For all the latest odds head to BetVictor.com - Be Lucky.