However, Town fans will be hoping it is not a case of déjà vu at the weekend - the Bees running out 5-1 winners last time the two sides met at the end of May.
In a nightmare showing, the Terriers shipped four goals in a dismal second-half showing to bring the curtain down on a season to forget for all concerned with the club.
Despite the poor end to the last campaign, the summer break has seen renewed optimism for Town fans with David Wagner signing no less than 12 new players to date.
There has also been a number of moves between both clubs through the years as well, with the top 4 club links outlined below.
4 Links between Huddersfield Town and Brentford
Struggling to make an impact at Huddersfield after signing from Watford in January 2009, the winger moved to fellow League One side Brentford on loan in January 2010.
However Ainsworth was shortly sent back to the Terriers after falling out with then-Bees boss Andy Scott before eventually sealing a permanent move to Shrewsbury Town in the summer of 2010.
After enduring an injury-hit 2009/10 for Huddersfield, the forward joined Brentford on loan for the duration of the following season, making 18 starts and scoring 8 goals.
However, on his return to the John Smith's Stadium Simpson was unable to break into the team, eventually sealing a move to Oldham Athletic.
A Huddersfield Town Academy Graduate, the striker struggled to break into the first-team and was sent out on a one-month loan to Brentford in October 2012.
Making only two appearances at Griffin Park, Spencer returned to the John Smith's Stadium and, after a number of other loan moves, eventually left the club in January 2014.
Before making his mark with Huddersfield, Rhodes featured for Brentford on a one-month loan deal from Ipswich Town.
After scoring twice in five league games, he came to the attention of then-Huddersfield manager Lee Clark who signed the forward for an undisclosed fee in July 2009.