The 48-year-old Scot will be hoping for an immediate reaction and could have quartet Ryan Shawcross, Glen Johnson, Erik Pieters and Geoff Cameron all available for his first game in charge after injury.
Meanwhile, Alex Pritchard may make his full Terriers debut following a substitute appearance in last week's disappointing 4-1 defeat against West Ham United.
Bringing you all the coverage from the Premier League clash at the bet365 Stadium is Blake Welton with expert analysis from Rory Benson.
FT: Stoke City 2 Huddersfield Town 0
The whistle blows in what is another disappointing afternoon for David Wagner’s men who slump to a six Premier League game without a win.
Second half strikes from Joe Allen and Mame Diouf earned Stoke City all three points with Town getting precariously closer to the bottom three with this result.
Stick with us though for all the post-match reaction and analysis, starting with the post-match press conference with both Town’s head coach David Wagner and his counterpart Paul Lambert.
90+2 Minutes: Choupo-Moting is replaced by Ramadan for the hosts.
Today’s attendance at the bet365 Stadium is 29,785 - apparently the highest recorded at the ground.
The fourth official indicates there will be a minimum of four additional minutes at the end of this game.
A minute of normal time remains here and Town look devoid of ideas with Stoke happy to see the game out.
83 Minutes: Stoke are looking to pick Town off on the counter; this time Shaqiri floats a cross towards Crouch but Schindler gets there first before Choupo-Moting volleys wide.
The German has now come down with a knock and, although back on his feet, is moving gingerly....
78 Minutes: Laurent Depoitre comes on for Jonathan Hogg - surely with 12 minutes to go it is too late??!!
77 Minutes: Peter Crouch replaces Mame Diouf - who trudges off the field slowly to milk the applause of the home faithful.
72 Minutes: Bauer is booked for pulling back Rajiv van La Parra near the corner flag.
Aaron Mooy’s free-kick is headed clear by Shawcross before Hogg fires the rebound well over the bar.
70 Minutes: Charlie Adam is replaced by Geoff Cameron for Stoke City.
Stoke City 2 Huddersfield Town 0
69 Minutes: Minutes later the Swiss forward is playing havoc again - his pass finds Diouf who makes it 2-0 with an expertly drilled effort which goes in off the post.
More Stoke Pressure...
67 Minutes: Stoke well and truly in the ascendancy here as Shaqiri counters again; beating Malone but his effort is drilled straight at Lossl.
62 Minutes: Choupo-Moting guides a header over the bar from the penalty spot after meeting a Moritz Bauer cross.
60 Minutes: Alex Pritchard is replaced by Abdelhamid Sabiri as Laurent Depoitre’s name is screamed out from the away end.
No sign of the big belgian forward just yet though....
59 Minutes: It’s all Stoke now as Town are really on the rack - Lossl denies Shaqiri and Diouf in the matter of minutes.
First Shaqiri beats the offside trap, cuts the ball onto his left foot but the Danish stopper is equal to it.
Then Diouf runs through but has a tight angle to contend with and his attempted pass across goal is cut out and deflected off him for a goal-kick.
56 Minutes: Collin Quaner comes on for Tom Ince as the Terriers have it all to do now.
Stoke City 1 Huddersfield Town 0
52 Minutes: I just turned to Rory to talk about no end-product from either side and Joe Allen goes and breaks the deadlock for Stoke City.
Choupo-Moting’s pull back was placed into the bottom corner by the the Welshman who arrived late into the box.
48 Minutes: The hosts have the ball in the net but Shaqiri’s acrobatic effort is ruled out for offside...
We’re back underway here at the Bet365 Stadium and there’s no changes at the interval.
Here’s how the first-half shaped up....
First Half Match Action...
HT: Stoke City 0 Huddersfield Town 0
The referee blows the whistle for the end of the first-half - it started out all Stoke City but Town appear to have weathered the storm without really threatening themselves.
The game then descended into a scrappy affair but going in with a draw at half-time will be encouraging for David Wagner’s men.
45 Minutes: Shaqiri is played over the top and through on goal - at first Jonas Lossl looks stranded in no-man’s land but he recovers well to stop the Swiss forward’s chipped effort.
The referee indicates there will be an additional minute to be added at the end of this half.
44 Minutes: Shaqiri whips a high floated free-kick into the area but the referee blows for a foul on Schindler by Shawcross.
The game is very scrappy at the moment but that will suit Town.
40 Minutes: Schindler has just been whipped clean out by Stoke’s Allen but referee Michael Oliver gives nothing for the offence.
Jeers of ‘You Don’t Know What You’re Doing’ ring out from the travelling away fans....
33 Minutes: It’s been a battle so far and Jonathan Hogg has been at the heart of it - he goes into the book for a foul on Maxim Choupo-Moting.
There was nothing in it but it was probably given for a few persistent fouls.