With both sides separated by just two points at the top of the SkyBet Championship table going into the game, there was more at stake than just local bragging rights.
In a combative opening first-half, substitute Izzy Brown opened the scoring for Town in the 27th minute before Chris Wood equalised for the visitors eight minutes later.
And as the game entered the final minutes, Michael Hefele scored a dramatic late winner - prodding home after Aaron Mooy's shot deflected into his path.
The goal sparked wild scenes of jubilations from Huddersfield Town with Head Coach David Wagner running onto the pitch to join his team's celebrations.
Those actions sparked fury from the visitors bench and as the German boss went to return to his own technical area an altercation began with Leeds United boss Garry Monk.
Soon both sets of staff and players were involved in a melee which occurred after a relatively trouble-free match, resulting in both bosses being sent to the stands and Leeds captain Liam Bridcutt and defender Pontus Jansson along with Elias Kachunga for Town all booked.
Watch the video grab above to see the touchline tussle at the end of a memorable win for Huddersfield Town at the John Smith's Stadium.