Huddersfield Town were hit by a late sucker punch as the head of Alan Browne condemned David Wagner's men to a fourth defeat on the spin.
The Terriers, backed by a vocal away following behind the goal, took the lead through Nahki Wells after dominating possession and chances during the first 80 minutes.
However, Preston equalised as the ball flew in off the unfortunate Joel Lynch, and Simon Grayson's men sensed blood.
As Town tried to hold on for the point which was the least their performance merited, Preston piled forward and got their reward when Alan Browne headed home at the far post in stoppage time.
There was still time for late controversy as Jonathan Hogg claimed his shot had gone over the line and Nahki Wells claimed a penalty but it was not to be.
Wagner will be desperate to see performances turn into points as soon as possible.
Here is what Town fans made of the game.
There was much excitement when the teams were announced, with fans delighted to see the inclusion of Philip Billing from the start.
More than 2000 fans away fans were loud, proud and getting plenty of attention.
As chances went begging despite dominating the ball, many fans began to predict the worst.
But after Nahki Wells scored only to see Preston find the net twice in reply, there was widespread disbelief.
There was frustration at missed chances and calls for a striker.
While others felt the defence needed reinforcements after two late goals conceded.
Unfortunately, a few felt it was simply "typical Town".