BBC Three has axed the award-winning show after two series due to budget cuts.
In a statement, the BBC said it couldn't afford to continue the drama and produce new shows.
Click below for pictures from the series
It said: "BBC Three is very proud of the two award-winning series of In The Flesh. However, given there is only budget for one original drama series a year on the channel it won’t be returning.
"We loved the show but have to make hard choice to bring new shows through and create room for emerging talent.
"Huge thanks to the BAFTA award-winning writer Dominic Mitchell and the superb cast."
The show had aired in both the UK and on BBC America, with scenes shot in Marsden for the second series in October 2013.
Starring Luke Newberry, the programme following troubled teen Kieren Walker, a PDS (Partially Deceased Syndrome) sufferer struggling to find acceptance and make peace with the living.
Kieren was one of several zombies trying to reintegrate into their homes and families, years after their deaths, after a freak accident brought them back to life.
BBC Three is due to close this autumn to become an online-only channel, as part of the BBC's budget cuts.